I can't grok what you're asking me but I'm almost certain the answer is no, as you've already inferred. Extrapolating DNS analytics to actionable intel is incredibly misleading in nearly every case on the service side, particularly since there are a number of caches that consider TTL a guideline and since large shared caches are commonplace.
Understanding what your company is doing if you run the resolver is where it makes more sense. But on the service side? You might as well hire a cat to report metrics by pawing a ouija board, and then you at least get cuddles with your random numbers.
Think of it this way: DNS is basically a different form of ARP, in a certain manner of speaking. I wouldn't try to quantify performance data from either except to troubleshoot operations.
If yahoo observes that every 1 in 3 yahoo.com requests in NS lookups then they could still figure out the traffic?
In practice.... i doubt this is valuable data at all.