I have a catch-all and can reply from any address I please. If I reply from an email sent to retailer@mydomain.com it even auto populates the "from" address for me with "retailer", or I can choose to reply from one of my named accounts. It's really slick.
I think the big downside for a lot of people is that it's hosted in the USA where the government is definitely headed in an autocratic direction that is abusive of most countries who don't comply to rantings from an orange madman. Definitely a huge downside.
I have a catch-all and can reply from any address I please. If I reply from an email sent to retailer@mydomain.com it even auto populates the "from" address for me with "retailer", or I can choose to reply from one of my named accounts. It's really slick.