The first time I took creatine (6g IIRC), I actually felt the mental effect just 2 minutes later. A pleasurable sensation of augmented presence and (mental) relaxation.
I paused taking that momentarily out of precaution while I wait some physical issue to normalize, but I plan to resume it in some weeks. Also it is considered a very safe supplement.
I've felt dehydrated while I'm in loading phase, it's very noticeable from that perspective. But the mental effects only come after at least a week (for me: longer attention span, less impacted by poor sleep).
Well.. I can't, nobody can. Perhaps it was a placebo effect or perhaps I had low levels of creatine and felt the difference. I often felt better right after taking it though, not consistently but often.
I paused taking that momentarily out of precaution while I wait some physical issue to normalize, but I plan to resume it in some weeks. Also it is considered a very safe supplement.