Does anyone know why such a fundamental gene would have such different behaviours between mammals?
> In previous mouse studies, loss of NANOG disrupted both the epiblast and the yolk sac - a tissue that supports the developing embryo. In this human embryo study, loss of NANOG primarily affected the epiblast, the future body-forming line of cells.
> In previous mouse studies, loss of NANOG disrupted both the epiblast and the yolk sac - a tissue that supports the developing embryo. In this human embryo study, loss of NANOG primarily affected the epiblast, the future body-forming line of cells.